Isopropanol → HCID 68118243, compound

Participants

Reaction Steps

4.2 g (0.015 mol) of 1-[2-methoxy-4-(2-methoxycarbonylaminovinyl)-phenoxy]-2,3-epoxy-propane are heated with a solution of 1.3 ml (0.016 mol) of isopropylamine in 100 ml of isopropanol to 80° C. under reflux for 3 hours. The mixture is then evaporated in vacuo and the resulting crude base is crystallised from acetone-ether. 1-[2-Methoxy-4-(2-methoxycarbonylaminovinyl)-phenoxy]-2-hydroxy-3-isopropyl-aminopropane, of melting point 109°-111° C. is obtained.

Provenance & Evidence