反应详情

The starting material is prepared as follows: The mixture of 50 g of 3-chlorobenzaldehyde, 41 g of malonic acid and 36 ml of pyridine is heated on the steam bath for 3 hours. The residue is dissolved in 200 ml of water, the solution acidified with hydrochloric acid, filtered, and the residue recrystallized from aqueous ethanol, to yield the 3-chlorocinnamic acid melting at 150°-152°.

1. customThe starting material is prepared
2. temperatureis heated on the steam bath for 3 hours
3. filtrationfiltered
4. customthe residue recrystallized from aqueous ethanol