HCID 15300849, compound → HCID 15300850, compound

HRID 259683Notes

Reaction equation

HRID 259683 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[S:11][N:10]=[C:9]([CH2:12][C:13]([O:15][CH3:16])=[O:14])[C:8]=2[CH:17]=1)([O-])=O>C(O)(=O)C.[Fe]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]2[S:11][N:10]=[C:9]([CH2:12][C:13]([O:15][CH3:16])=[O:14])[C:8]=2[CH:17]=1

Participants

4

Reactant 1

HCID 15300849HCID 15300849, compound

Product 1

HCID 15300850HCID 15300850, compound

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 176Acetic AcidSolvent

Conditions

Temperature
50 °C

Procedure

Iron (0.74 g, 13.3 mmol) is added portionwise to a solution of methyl 5-nitro-1,2-benzisothiazole-3-acetate (0.67 g, 2.7 mmol) in acetic acid at 50° C. The reaction mixture is stirred at 50° C. for several minutes, cooled and filtered through diatomaceous earth. The resultant filtrate, which contains the title product, is used in Example 22 without further purification.

Workup

  1. temperaturecooled
  2. filtrationfiltered through diatomaceous earth
  3. customis used in Example 22 without further purification

Sources & evidence

ORD record
ord-3fec88dd939c450e8a545d33f72591b1
Source dataset
uspto-grants-1996_06
Patent number
US05523278

Reaction notes

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