反应详情

Dry NH3 gas is passed through 48.9 g (0.30 mol) of methyl 2-chloro-3-oxovalerate at 70° C. for a period of 2 h. After removal of volatile constituents in vacuo, the crude product is dissolved in diisopropyl ether and washed with a little ice water. After drying over MgSO4, the solvent is removed in vacuo. Yield: 80.0% [GC]

1. customAfter removal of volatile constituents in vacuo
2. dissolutionthe crude product is dissolved in diisopropyl ether
3. washwashed with a little ice water
4. dry with materialAfter drying over MgSO4
5. customthe solvent is removed in vacuo