HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-chloro-3-oxopentanoate → Methyl 3-amino-2-chloro-2-pentenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-chloro-3-oxopentanoate | HCID 545096 | — |
| Reactant | Ammonium formate | HCID 2723923 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Methyl 3-amino-2-chloro-2-pentenoate | HCID 86749529 | 72% |
Reaction Steps
A solution of 47.5 g (0.75 mol) of ammonium formate and 49.0 g (0.3 mol) of methyl 2-chloro-3-oxovalerate in 800 ml of ethanol is reacted and worked up in analogy to Example 2. Yield: 72.0% [GC]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05523404 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-0b8c90080f24455b82d46f1bfdd0c91b |
| Source note | uspto-grants-1996_06 |