Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 259809Generated: October 26, 2026

Formamide → HCID 178440190, compound

https://huagongshe.com/reaction/259809

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormamideHCID 713—
ReactantSodium MethoxideHCID 10942334—
ReactantEthyl 3-amino-2-chloro-4-methyl-2-pentenoateHCID 86749531—
SolventMethanolHCID 887—
ProductHCID 178440190HCID 178440190—

Reaction Steps

45.1 g (0.24 mol) of ethyl 3-amino-2-chloro-4-methyl-2-pentenoate are reacted with 36.8 g (0.59 mol) of formamide and 109 ml of sodium methylate solution in 130 ml of methanol and worked up in analogy to Example 9. Yield: 34.5 g (83.3%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05523404
Source datasetuspto-grants-1996_06
ORD IDord-86673681deba450884fd73d84e02cc07
Source noteuspto-grants-1996_06