HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutyraldehyde → 1-Benzhydrylamino-2-methylpropanephosphonous acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutyraldehyde | HCID 6561 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | HCID 178527021 | HCID 178527021 | — |
| Product | 1-Benzhydrylamino-2-methylpropanephosphonous acid | HCID 21325882 | — |
Reaction Steps
7.2 parts of isobutyraldehyde in 15 parts of sodium-dried dioxan was added to a suspension of 25 parts of benzhydrylammonium hypophosphite in 150 parts of sodium-dried dioxan under reflux. 80 Parts of dioxan was removed and 150 parts of alcohol added. After cooling the mixture was filtered to give DL-1-benzhydrylamino-2-methylpropanephosphonous acid, melting point 189°-192° identical to that obtained in Example 2A.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04147780 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-3844a011b0f64d7dae493464f93e978b |
| Source note | uspto-grants-1979_04 |