Bicyclo(3.2.1)octane-2,4-dione → 3-(2-Nitro-4-methylsulfonylbenzoyl)bicyclo[3.2.1]octane-2,4-dione

HRID 260020Notes

Reaction equation

HRID 260020 reaction equation
[CH:1]12[CH2:8][CH:5]([CH2:6][CH2:7]1)[C:4](=[O:9])[CH2:3][C:2]2=[O:10].[N+:11]([C:14]1[CH:22]=[C:21]([S:23]([CH3:26])(=[O:25])=[O:24])[CH:20]=[CH:19][C:15]=1[C:16](Cl)=[O:17])([O-:13])=[O:12]>ClCCl>[N+:11]([C:14]1[CH:22]=[C:21]([S:23]([CH3:26])(=[O:25])=[O:24])[CH:20]=[CH:19][C:15]=1[C:16]([CH:3]1[C:4](=[O:9])[CH:5]2[CH2:8][CH:1]([CH2:7][CH2:6]2)[C:2]1=[O:10])=[O:17])([O-:13])=[O:12]

Participants

4

Reactant 2

HCID 144686Bicyclo(3.2.1)octane-2,4-dioneHCID 148001864-(Methanesulfonyl)-2-nitrobenzoyl chloride

Product 1

HCID 157908003-(2-Nitro-4-methylsulfonylbenzoyl)bicyclo[3.2.1]octane-2,4-dione

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

To a solution of 10 g of bicyclo[3.2.1]octane-2,4-dione in 100 ml of dichloromethane was added dropwise 70 ml of a dichloromethane solution having dissolved therein 19.1 g of 2-nitro-4-methylsulfonylbenzoyl chloride while ice cooling.

Workup

  1. dissolutionhaving dissolved

Sources & evidence

ORD record
ord-66611ccc48004ec8919b71f4a7e45176
Source dataset
uspto-grants-1996_06
Patent number
US05525580

Reaction notes

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