HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylthiocarbamoyl chloride → Dimethylthiocarbamoyl valine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylthiocarbamoyl chloride | HCID 27871 | — |
| Reactant | l-Valine, ethyl ester | HCID 87182 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | Dimethylthiocarbamoyl valine | HCID 53885838 | — |
Reaction Steps
Valine ethyl ester (0.0028 mol) in 10 ml acetonitrile was reacted with dimethylthiocarbamoyl chloride (0.0056 mol) at 50° C. for 2 hours. Solvent acetonitrile was removed by rotary evaporation. Trifluoroacetic acid (10 ml) was added and the mixture stirred at room temperature for 15 min. The trifluoroacetic acid was removed by rotary evaporation. The residue was dissolved in water and analyzed by FAB/MS. The expected product, dimethylthiocarbamoyl valine (MH+=205), was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05525707 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-7c3f4ac9582a492d88c902c8d1fa939d |
| Source note | uspto-grants-1996_06 |