1-Hexanol → HCID 21708618, compound

HRID 260361Notes

Reaction equation

HRID 260361 reaction equation
[Cl:1][C:2]1[CH:9]2[CH2:10][N:5]([CH2:6][CH2:7][CH2:8]2)[CH2:4][C:3]=1[C:11]1[C:12](Cl)=[N:13][S:14][N:15]=1.[CH2:17]([OH:23])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]>>[ClH:1].[Cl:1][C:2]1[CH:9]2[CH2:10][N:5]([CH2:6][CH2:7][CH2:8]2)[CH2:4][C:3]=1[C:11]1[C:12]([O:23][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[N:13][S:14][N:15]=1

Participants

3

Reactant 2

HCID 81031-HexanolHCID 9856832HCID 9856832, compound

Product 1

HCID 21708618HCID 21708618, compound

Procedure

The compound was made as described in example 44 by reacting 4-chloro-3-(3-chloro-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.3.1]non-3-ene with 1-hexanol. The free base was crystallized as the hydrochloride from ether. (Compound 94). M.p. 100°-101° C.

Workup

  1. customThe free base was crystallized as the hydrochloride from ether

Sources & evidence

ORD record
ord-9573c263a8fe46b09657cb89a9cc408c
Source dataset
uspto-grants-1996_06
Patent number
US05527813

Reaction notes

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