HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyisonicotinonitrile → (2-Methoxypyridin-4-yl)methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyisonicotinonitrile | HCID 7204887 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (2-Methoxypyridin-4-yl)methanamine | HCID 16227983 | — |
Reaction Steps
A solution of 4-cyano-2-methoxypyridine (0.55 g, 4.1 mmol) in ethanol was hydrogenated at 60 psi H2 in the presence of 10% Pd/C (100 mg). After 3.5 h the catalyst was removed by filtration through Super-Gel and the liltrate evaporated to give the title compound as a foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05527819 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-3fa0020c6e9c4e56a9b2fcba963c000d |
| Source note | uspto-grants-1996_06 |