huagongshe.com
HRID260496

反应详情

EQUATION

反应方程式

HRID 260496 的结构方程式

REACTANTS

反应物

2
结构：N#CN
HCID9864

Cyanamide

CH2N2

结构：CCOC(=N)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1
HCID135761968

未命名化合物

PRODUCTS

生成物

1
结构：N#CNC(=N)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1
HCID178512305

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Ethyl 5-chloro-3-phenylsulfonylindole-2-carboximidate is reacted with an equimolar amount of cyanamide in absolute methanol (according to the procedure of K. R. Huffman and F. C. Schaefer (J. Org. Chem., 28, 1812 (1963)). After 30-60 minutes the solvent is removed and the residue purified by silica gel chromatography to afford the title compound.

WORKUP

后处理

  1. customAfter 30-60 minutes the solvent is removed
  2. customthe residue purified by silica gel chromatography