HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-butylindole-3-carboxylic Acid → Indole-3-Carboxylic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-butylindole-3-carboxylic Acid | HCID 10376290 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | Indole-3-Carboxylic Acid | HCID 69867 | — |
Reaction Steps
reacting the 4-bromomethyl-2'-[2-(1-methyl-1-phenylethyl)-2H-tetrasol-5-yl]biphenyl with 2-transmetalated 1-but-1-yl-1H-indole-3-carboxylic acid in the presence of phosphinated palladium catalyst to give 1-butyl-2-[2'-92-(1-methyl-1-phenylethyl)-2H-tetrasol-5-yl)biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid; and
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05527918 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-6e79d3253feb40d1b677e849f6165dca |
| Source note | uspto-grants-1996_06 |