HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-(3-benzyloxycarbonyl-1-indolyl)-butyrate → 1-(3-Ethoxycarbonylpropyl)indole-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-(3-benzyloxycarbonyl-1-indolyl)-butyrate | HCID 22400494 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(3-Ethoxycarbonylpropyl)indole-3-carboxylic acid | HCID 22400472 | — |
Reaction Steps
A mixture of ethyl 4-(3-benzyloxycarbonyl-1-indolyl)-butyrate and 10% palladium carbon in ethanol was stirred at room temperature for 1.5 hours under a hydrogen atmosphere. Removal of the catalyst and evaporation of the solvent afforded the object product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05530019 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-986e4b6206814c219fb52f8130a34804 |
| Source note | uspto-grants-1996_06 |