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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 260921Generated: October 30, 2026

Formanilide → 2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl-N-formylaniline

https://huagongshe.com/reaction/260921

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormanilideHCID 7671—
Reactant5-(2-Chloroethyl)-1-azabicyclo[3.3.0]octaneHCID 10702365—
Product2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl-N-formylanilineHCID 10706378—

Reaction Steps

The procedures described in Example 2 were repeated except that formanilide (1.80 g, 14.9 mmol) and 5-(2-chloroethyl)-1-azabicyclo[3.3.0]octane (hydrochloride, 3.43 g, 16.3 mmol ) were employed. In this case, the desired compound was obtained as a pale yellow liquid (3.39 g, 88.1 %).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05530138
Source datasetuspto-grants-1996_06
ORD IDord-adcc6dbf198a4cb18228d5848a3612aa
Source noteuspto-grants-1996_06