HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formanilide → 2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl-N-formylaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formanilide | HCID 7671 | — |
| Reactant | 5-(2-Chloroethyl)-1-azabicyclo[3.3.0]octane | HCID 10702365 | — |
| Product | 2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl-N-formylaniline | HCID 10706378 | — |
Reaction Steps
The procedures described in Example 2 were repeated except that formanilide (1.80 g, 14.9 mmol) and 5-(2-chloroethyl)-1-azabicyclo[3.3.0]octane (hydrochloride, 3.43 g, 16.3 mmol ) were employed. In this case, the desired compound was obtained as a pale yellow liquid (3.39 g, 88.1 %).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05530138 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-adcc6dbf198a4cb18228d5848a3612aa |
| Source note | uspto-grants-1996_06 |