1-Chloro-2-nitrobenzene → HCID 10493669, compound

HRID 260926Notes

Reaction equation

HRID 260926 reaction equation
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].[CH3:11][NH:12][CH2:13][CH2:14][C:15]12[CH2:22][CH2:21][CH2:20][N:19]1[CH2:18][CH2:17][CH2:16]2>>[N:19]12[CH2:20][CH2:21][CH2:22][C:15]1([CH2:14][CH2:13][N:12]([CH3:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9])[CH2:16][CH2:17][CH2:18]2

Participants

3

Reactant 2

HCID 69451-Chloro-2-nitrobenzeneHCID 10559044HCID 10559044, compound

Product 1

HCID 10493669HCID 10493669, compound

Procedure

The procedures described in Example 12 were repeated except that 1-chloro-2-nitrobenzene (1.87 g, 11.9 mmol) and 5-(2-methylaminoethyl)-1-azabicyclo[3.3.0]octane (4.00 g, 28.8 mmol) were employed. In th is case, the desired compound was obtained as a orange liquid (2.95 g, 85.7%).

Sources & evidence

ORD record
ord-7e36a52947a342feb859cfc997a14faa
Source dataset
uspto-grants-1996_06
Patent number
US05530138

Reaction notes

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