Acetyl chloride → HCID 135702346, compound

Participants

Reaction Steps

Acetyl chloride (3.8 g) was added slowly to a suspension of 2-methyl-3-amino-6-t-butyl-2,5-dihydropyrazolo[3,4-d]-pyrimidin-4-one (10.5 g) in pyridine (50 ml). The solution was left to cool overnight and then concentrated to an oil which was dissolved in 0.5 N hydrochloric acid (20 ml). Scratching induced crystallisation. The precipitate was recrystallised from 80:20 ethanol:water (1.5 g, 12%) m.p. 340°-42° decomposition.

Provenance & Evidence