反应详情

A mixture of 785 mg (3.3 mmole) of N-(2,3-dihydroxypropionyl)-3-amino-5-nitroaniline and 690 mg (3.3 mmole) of 3,5-diacetyl-4,6-dihydroxy-2H-pyran-2-one in 30 ml of methanol was heated under reflux for 30 minutes. After cooling, the crystalline product was filtered and dried in vacuum to give 616 mg of 5-acetyl-4-hydroxy-3-[1-(3-glyceroylamino-5-nitrophenylamino)ethylidene]-2H-pyran-2,6(3H)-dione.

1. temperaturewas heated
2. temperatureunder reflux for 30 minutes
3. temperatureAfter cooling
4. filtrationthe crystalline product was filtered
5. customdried in vacuum