3,4-Dichloroaniline → 1-(2,6-Dichlorobenzoyl)-3-(3,4-dichlorophenyl)thiourea

HRID 261481Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 261481
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([Cl:11])[C:3]=1[C:4](Cl)=[O:5].[C:12]([SH:14])#[N:13].N.[Cl:16][C:17]1[CH:18]=[C:19]([CH:21]=[CH:22][C:23]=1[Cl:24])[NH2:20]>CC(C)=O.O>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([Cl:11])[C:3]=1[C:4]([NH:13][C:12]([NH:20][C:19]1[CH:21]=[CH:22][C:23]([Cl:24])=[C:17]([Cl:16])[CH:18]=1)=[S:14])=[O:5]

Komponenten

6

Edukt 3

HCID 72573,4-DichloroanilineHCID 783922,6-Dichlorobenzoyl chlorideHCID 13417437Amthio

Produkt 1

HCID 190064161-(2,6-Dichlorobenzoyl)-3-(3,4-dichlorophenyl)thiourea

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 180AcetoneLösungsmittel2×HCID 962WaterLösungsmittel

Versuchsvorschrift

10.5 g of 2,6-dichlorobenzoylchloride are added drop by drop with stirring to a solution of 3.8 g of ammonium rhodanide in 15 ml of acetone. After boiling for 15 minutes the reaction mixture is added drop by drop to a solution of 8.1 g of 3,4-dichloroaniline in 15 ml of acetone. After stirring for 30 minutes the reaction mixture is poured in water and extracted with ether. The ethereal solution is dried and concentrated by evaporation and the residue is taken up in benzene. After working up and decrystallizing from benzene 1.3 g of the superscribed substance is obtained. Melting point 240° C.

Aufarbeitung

  1. extractionextracted with ether
  2. customThe ethereal solution is dried
  3. concentrationconcentrated by evaporation
  4. customis obtained

Quellen und Nachweise

ORD-Eintrag
ord-393a5fcecec54082bb5a377ca131f8df
Quelldatensatz
uspto-grants-1979_08
Patentnummer
US04166124

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