HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-(chloromethyl)-2-fluoro- → HCID 20394266, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-(chloromethyl)-2-fluoro- | HCID 9580 | — |
| Reactant | 1-Methyl-4-piperidone | HCID 74049 | — |
| Product | HCID 20394266 | HCID 20394266 | — |
Reaction Steps
A sample of 2-fluorobenzyl chloride is converted to its Grignard reagent as described in Example 1 and is reacted with a sample of N-methyl-4-piperidone to provide 1-methyl-4-(2-fluorobenzyl)-4-piperidinol, mp 93°-95° C., after two recrystallizations.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04166119 |
| Source dataset | uspto-grants-1979_08 |
| ORD ID | ord-7bbce914c6564b959f130f94fe6a727b |
| Source note | uspto-grants-1979_08 |