HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 2,2,alpha-Trimethyl-5-indanacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Cyclohexylammonium Ion | HCID 1549093 | — |
| Reactant | 2,2,alpha-Trimethyl-5-indanacetic acid methyl ester | HCID 53993724 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2,2,alpha-Trimethyl-5-indanacetic acid | HCID 13239894 | — |
Reaction Steps
17 g of 2,2,α-trimethyl-5-indanacetic acid methyl ester are saponified together with 8.2 g of potassium hydroxide in 160 cc of methanol and 16 cc of water in a manner analogous to that described in Example 25. After working up the reaction mixture, oily 2,2,α-trimethyl-5-indanacetic is obtained. The cyclohexylammonium salt of the title compound has a M.P. of 180°-183° (from ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04166131 |
| Source dataset | uspto-grants-1979_08 |
| ORD ID | ord-3cf2243ff8c1488893eed87595bf3387 |
| Source note | uspto-grants-1979_08 |