2-chloro-N,N-dimethylacetamide → 2-{7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-5-hydroxy-10,10-dimethyl-1,2,4,10-tetrahydro-9-oxa-3-aza-phenanthren-3-yl}-N,N-dimethyl-acetamide

Participants

Role	Name	HCID	Charge
Reactant	2-chloro-N,N-dimethylacetamide	HCID 75886	—
Reactant	5,5-dimethyl-8-[5-(4-fluorophenyl)-2-pentyl]-10-hydroxy-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-d]pyridine	HCID 12800741	—
Product	2-{7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-5-hydroxy-10,10-dimethyl-1,2,4,10-tetrahydro-9-oxa-3-aza-phenanthren-3-yl}-N,N-dimethyl-acetamide	HCID 21321141	—

Reaction Steps

The above-titled compound was prepared by reacting 8-[5-(4-fluorophenyl)-2-pentyl]-10-hydroxy-5,5-dimethyl-1,2,3,4-tetrahydro-5H-[1]benzopyrano[4,3-c]pyridine with 2-chloro-N,N-dimethylacetamide according to the method of Example 3.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04152327
Source dataset	uspto-grants-1979_05
ORD ID	ord-32d1c15572f645c882d944a33dc50353
Source note	uspto-grants-1979_05