反应详情

p-Toluidine (0.20 mole), acetophenone (0.20 mole), and IRC-50 (weakly acidic) ion exchange resin (0.5 g.) are azeotropically refluxed in toluene (150 cc). The required amount of water is removed after 3 hrs. The solvent is removed on the rotary, and the residue is distilled under reduced pressure to give N-(methylbenzylidene)-p-toluidine. b.p. 129°-37° C./0.05 mm.

1. customThe required amount of water is removed after 3 hrs
2. customThe solvent is removed on the rotary, and the residue
3. distillationis distilled under reduced pressure