反应详情

A mixture of 103 g. of 5-bromovaleric acid and 152 g. of triphenylphosphine in 400 ml. of acetonitrile is refluxed for 48 hours, cooled, diluted with 100 ml. of benzene and allowed to crystallize. The crystals are filtered, washed with benzene and ether, to yield colorless material, m.p. 207°-209° C.

1. additionA mixture of 103 g
2. temperaturecooled
3. additiondiluted with 100 ml
4. customto crystallize
5. filtrationThe crystals are filtered
6. washwashed with benzene and ether
7. customto yield colorless material, m.p. 207°-209° C.