反应详情

A mixture of 10 g. (0.0227 mol) of α,α-bis(p-fluorophenyl)-1-(toluene-p-sulphonyl)imidazole-2-methanol, 34 ml. of 2 N hydrochloric acid solution (0.0681 mol) and 225 ml. of water was boiled under reflux for 5 hours. After cooling, the mixture was made alkaline by addition of ammonia. The base obtained was crystallised from isopropyl alcohol; its melting point was 198°-200° C.

1. additionA mixture of 10 g
2. temperatureunder reflux for 5 hours
3. temperatureAfter cooling
4. customThe base obtained
5. customwas crystallised from isopropyl alcohol