2-Nitrophenol → HCID 14771304, compound

HRID 262017Notes

Reaction equation

Br[CH:2]1[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.[N+:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[OH:17])([O-:10])=[O:9]>>[CH:2]1([O:17][C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[N+:8]([O-:10])=[O:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

Reactant 2

HCID 69472-Nitrophenol

HCID 7960Cyclohexyl bromide

Product 1

HCID 14771304HCID 14771304, compound

Procedure

In a similar manner as in Example 1, bromocyclohexane was reacted with o-nitrophenol to yield 2-cyclohexoxynitrobenzene; which was reduced to the corresponding aniline; then reacted with N-methylolpyrrolidone to form the corresponding N-methylenepyrrolidonyl derivative; which was acylated with chloroacetyl chloride to form the desired product.

Sources & evidence

ORD record: ord-51a3b8231d42414b90360647b8dffa23
Source dataset: uspto-grants-1979_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04153446

Reaction notes

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