HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Sulfide → HCID 12526353, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Sulfide | HCID 402 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Amino-2-(methylsulfanyl)-1,3-thiazole-5-carbonitrile | HCID 676411 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 12526353 | HCID 12526353 | 54% |
Reaction Steps
20 parts of hydrogen sulfide are introduced, over 6 hours, into a mixture of 51.3 parts of 2-methylmercapto-4-amino-5-cyanothiazole, 0.2 part of triethylamine and 150 parts of dimethylformamide. The reaction mixture is left to stand for 48 hours and is then poured into 500 parts of ice water, and the product is filtered off. 33 parts of 2-methylmercapto-4-amino-5-thiocarbamoylthiazole (54% of theory) of melting point 192°-195° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153607 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-57a519576cd049aa94634a65d63f5110 |
| Source note | uspto-grants-1979_05 |