HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Sulfide → 2-Pyrrolidino-4-amino-5-thiocarbamoylthiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Sulfide | HCID 402 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | HCID 12526351 | HCID 12526351 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 2-Pyrrolidino-4-amino-5-thiocarbamoylthiazole | HCID 12526354 | 53% |
Reaction Steps
25 parts of 2-pyrrolidino-4-amino-5-cyanothiazole are reacted with 8 parts of hydrogen sulfide in 150 parts of dimethylformamide and 2 parts of triethylamine, by the method described in Example 1(a). 15.6 parts of 2-pyrrolidino-4-amino-5-thiocarbamoyl-thiazole (53% of theory) of melting point 264°-265° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153607 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-c6df370ae3104f9796cc2fd91f1131c9 |
| Source note | uspto-grants-1979_05 |