反应详情

25 parts of 2-pyrrolidino-4-amino-5-cyanothiazole are reacted with 8 parts of hydrogen sulfide in 150 parts of dimethylformamide and 2 parts of triethylamine, by the method described in Example 1(a). 15.6 parts of 2-pyrrolidino-4-amino-5-thiocarbamoyl-thiazole (53% of theory) of melting point 264°-265° C. are obtained.