HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 262033Generated: October 31, 2026
Hydrogen Peroxide → 3-Amino-5-pyrrolidino-thiazolo-(4,5-c)-isothiazole
https://huagongshe.com/reaction/262033
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | 2-Pyrrolidino-4-amino-5-thiocarbamoylthiazole | HCID 12526354 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-Amino-5-pyrrolidino-thiazolo-(4,5-c)-isothiazole | HCID 12526370 | — |
Reaction Steps
5 parts of 2-pyrrolidino-4-amino-5-thiocarbamoylthiazole prepared as described in Example 3(a) and 3(b) are suspended in 50 parts of glacial acetic acid and 1 part of 50 percent strength by weight hydrogen peroxide is added at 20° C. Thereupon, the temperature rises to 30° C. After stirring for one hour at 22° C., the end product is precipitated by means of 100 parts of water, and is filtered off. 4.1 parts (82% of theory) of melting point 262°-264° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04153607 |
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| Source dataset | uspto-grants-1979_05 |
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| ORD ID | ord-6877cc034124450ab2b0f2d7529bbcb2 |
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| Source note | uspto-grants-1979_05 |
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