反应详情

温度

22 °C

5 parts of 2-pyrrolidino-4-amino-5-thiocarbamoylthiazole prepared as described in Example 3(a) and 3(b) are suspended in 50 parts of glacial acetic acid and 1 part of 50 percent strength by weight hydrogen peroxide is added at 20° C. Thereupon, the temperature rises to 30° C. After stirring for one hour at 22° C., the end product is precipitated by means of 100 parts of water, and is filtered off. 4.1 parts (82% of theory) of melting point 262°-264° C. are obtained.

1. additionis added at 20° C
2. customrises to 30° C
3. customthe end product is precipitated by means of 100 parts of water
4. filtrationis filtered off
5. custom4.1 parts (82% of theory) of melting point 262°-264° C. are obtained