HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Sulfide → 2-Phenyl-4-amino-5-thiocarbamoylthiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Sulfide | HCID 402 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 4-Amino-2-phenyl-1,3-thiazole-5-carbonitrile | HCID 12526352 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 2-Phenyl-4-amino-5-thiocarbamoylthiazole | HCID 12526355 | 89% |
Reaction Steps
75 parts of 2-phenyl-4-amino-5-cyanothiazole in 300 parts of dimethylformamide and 15 parts of triethylamine are reacted with 13 parts of hydrogen sulfide as described in Example 1(a). 77 parts of 2-phenyl-4-amino-5-thiocarbamoylthiazole (89% of theory) of melting point 164°-167° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153607 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-d00c3903127941638ec2242bf6843463 |
| Source note | uspto-grants-1979_05 |