Hydrogen Peroxide → HCID 21319832, compound

HRID 262038Notes

Reaction equation

HRID 262038 reaction equation
[CH3:1][C:2]1[S:3][C:4]([C:8](=[S:10])[NH2:9])=[C:5]([NH2:7])[N:6]=1.OO>C(O)(=O)C>[NH2:9][C:8]1[S:10][N:7]=[C:5]2[N:6]=[C:2]([CH3:1])[S:3][C:4]=12

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 21319836HCID 21319836, compound

Product 1

HCID 21319832HCID 21319832, compoundYield 50%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
22 °C

Procedure

3.4 parts of 2-methyl-4-amino-5-thiocarbamoyl-thiazole are suspended in 50 parts of glacial acetic acid and one part of 30 percent strength by weight hydrogen peroxide is added. After stirring for 12 hours at 22° C., the product is filtered off. 1.7 parts of 3-amino-5-methyl-thiazolo-(4,5-c)-isothiazole (50% of theory) of melting point 164°-167° C. are obtained.

Workup

  1. additionis added
  2. filtrationthe product is filtered off

Sources & evidence

ORD record
ord-7635e19d6f3b45b5a16ec74e21cf41ea
Source dataset
uspto-grants-1979_05
Patent number
US04153607

Reaction notes

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