Phenacyl bromide → HCID 21319938, compound

HRID 262083Notes

Reaction equation

HRID 262083 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[OH:9].Br[CH2:11][C:12]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=O>>[CH3:8][C:6]1[CH:7]=[C:2]([CH3:1])[C:3]2[O:9][CH:11]=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:4]=2[CH:5]=1

Participants

3

Reactant 2

HCID 6259Phenacyl bromideHCID 77712,4-Dimethylphenol

Product 1

HCID 21319938HCID 21319938, compound

Procedure

Using the method of Example 17 and starting with 2,4-dimethylphenol and α-bromoacetophenone and cyclizing at 50°-60° C., 5,7-dimethyl-3-phenylbenzofuran is obtained.

Sources & evidence

ORD record
ord-66075a8250a442a79e625f5a5a5b916a
Source dataset
uspto-grants-1979_05
Patent number
US04153619

Reaction notes

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