Bromine → 2,7-Dibromo-5-methyl-3-phenylbenzofuran

HRID 262090Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 262090
[Br:1][C:2]1[C:10]2[O:9][CH:8]=[C:7]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)[C:6]=2[CH:5]=[C:4]([CH3:17])[CH:3]=1.[Br:18]Br>ClCCl>[Br:18][C:8]1[O:9][C:10]2[C:2]([Br:1])=[CH:3][C:4]([CH3:17])=[CH:5][C:6]=2[C:7]=1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Komponenten

4

Edukt 2

HCID 24408BromineHCID 213199287-Bromo-5-methyl-3-phenylbenzofuran

Produkt 1

HCID 213199312,7-Dibromo-5-methyl-3-phenylbenzofuran

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

A solution of 86.6 g. (0.30 mole) of 7-bromo-5-methyl-3-phenylbenzofuran in 600 ml. of dichloromethane is treated dropwise over 45 minutes with 47.9 g. (0.30 mole) of bromine. After stirring one additional hour, the mixture is washed once with water (300 ml.) and thrice with 300 ml. portions of saturated sodium bicarbonate solution, dried, then evaporated to provide 2,7-dibromo-5-methyl-3-phenylbenzofuran as an oil which crystallizes from hexane.

Aufarbeitung

  1. washthe mixture is washed once with water (300 ml.) and thrice with 300 ml
  2. dry with materialportions of saturated sodium bicarbonate solution, dried
  3. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-45af32458b9b42cdbefb3d7587beec74
Quelldatensatz
uspto-grants-1979_05
Patentnummer
US04153619

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