HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Phenyl-2-[4-(3,4,5-trimethoxy-benzoyl)-1-piperazinyl]-indole 3-carboxylic acid 4-methyl-piperazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-(3,4,5-Trimethoxybenzoyl)piperazine | HCID 2874204 | — |
| Reactant | HCID 85906066 | HCID 85906066 | — |
| Product | 1-Phenyl-2-[4-(3,4,5-trimethoxy-benzoyl)-1-piperazinyl]-indole 3-carboxylic acid 4-methyl-piperazide | HCID 86736460 | — |
Reaction Steps
This compound was prepared from 2-chloro-1-phenyl-indole 3-carboxylic acid 4-methyl-piperazide and 3,4,5-trimethoxy benzoic acid piperazide in boiling diglym according to Examples 7, 40, 42 and 45. The yield of amorphous product amounted to 77% of the theoretical yield. The hydrochloride melted at 253°-255° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04148895 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-acfc8966c88142258d2c633c82f69485 |
| Source note | uspto-grants-1979_04 |