Tert-Butylamine → HCID 86736532, compound

HRID 262490Notes

Reaction equation

HRID 262490 reaction equation
[CH3:1][N:2]1[C:11]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH:20]3[O:22][CH2:21]3)=[CH:14][CH:13]=2)=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]1=[O:23].[C:24]([NH2:28])([CH3:27])([CH3:26])[CH3:25]>>[CH3:1][N:2]1[C:11]([C:12]2[CH:13]=[CH:14][C:15]([O:18][CH2:19][CH:20]([OH:22])[CH2:21][NH:28][C:24]([CH3:27])([CH3:26])[CH3:25])=[CH:16][CH:17]=2)=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]1=[O:23]

Participants

3

Reactant 2

HCID 6385Tert-ButylamineHCID 21319074HCID 21319074, compound

Product 1

HCID 86736532HCID 86736532, compoundYield 84%

Procedure

2-Methyl-3-[4-(2-hydroxy-3-tert. butylamino-propoxy)-phenyl]-isoquinolin-1(2H)-one was prepared analogous to Example 1b from 2-methyl-3-[4-(2,3-epoxypropoxy)-phenyl]-isoquinolin-1(2H)-one and tert. butylamine.

Sources & evidence

ORD record
ord-7e310d72a08c410c9c11c619e374df89
Source dataset
uspto-grants-1979_05
Patent number
US04154837

Reaction notes

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