4-Fluorobenzylamine → HCID 54242806, compound

HRID 262543Notes

Reaction equation

HRID 262543 reaction equation
O=[C:2]([CH:13]([CH3:15])[CH3:14])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]([OH:12])=[O:11].[F:16][C:17]1[CH:24]=[CH:23][C:20]([CH2:21][NH2:22])=[CH:19][CH:18]=1>[Pt]>[F:16][C:17]1[CH:24]=[CH:23][C:20]([CH2:21][NH:22][CH:2]([CH:13]([CH3:15])[CH3:14])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]([OH:12])=[O:11])=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 673264-FluorobenzylamineHCID 21319328HCID 21319328, compound

Product 1

HCID 54242806HCID 54242806, compound

Reagents, catalysts & solvents 1

HCID 23939PlatinumCatalyst

Procedure

Using the procedure of example I step D and starting from 9-oxo 10-methyl undecanoic acid and para fluorobenzylamine then hydrogenating in the presence of a platinum catalyst dl 9-(para fluorobenzylamino) 10-methyl undecanoic acid is obtained melting at 78°-82° after recrystallisation from acetonitrile.

Workup

  1. customis obtained melting at 78°-82°
  2. customafter recrystallisation from acetonitrile

Sources & evidence

ORD record
ord-c3024313afda4ae48d6e1b043c486922
Source dataset
uspto-grants-1979_05
Patent number
US04154851

Reaction notes

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