Ammonia → 1-[2-(Dimethylamino)ethyl]-1,4-cyclohexadiene

HRID 26265Notes

Reaction equation

HRID 26265 reaction equation
[CH3:1][N:2]([CH3:11])[CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[Li].N>C(O)C>[CH3:11][N:2]([CH3:1])[CH2:3][CH2:4][C:5]1[CH2:10][CH:9]=[CH:8][CH2:7][CH:6]=1

Participants

5

Reactant 3

HCID 222AmmoniaHCID 25125N,N-DimethylphenylethylamineHCID 3028194Lithium

Product 1

HCID 122289201-[2-(Dimethylamino)ethyl]-1,4-cyclohexadiene

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

45 g. (0.3 moles) of the dimethylphenethylamine is reduced by treatment with 16 g. of lithium (2.3 g. atom) in 1.5 l. of ammonia and 250 ml. of ethanol according to the procedure of Example 1(a) to yield crude 1-[2-(dimethylamino)ethyl]-1,4-cyclohexadiene.

Sources & evidence

ORD record
ord-d981f93023c54880b523e533bbef7a0b
Source dataset
uspto-grants-1979_04
Patent number
US04149001

Reaction notes

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