Cysteamine → 3-[(2-Aminoethyl)thiomethyl]-5-chloro-1,2,4-thiadiazole

HRID 262684Notes

Reaction equation

HRID 262684 reaction equation
[Cl:1][C:2]1[S:6][N:5]=[C:4]([CH2:7]Cl)[N:3]=1.[NH2:9][CH2:10][CH2:11][SH:12]>>[NH2:9][CH2:10][CH2:11][S:12][CH2:7][C:4]1[N:3]=[C:2]([Cl:1])[S:6][N:5]=1

Participants

3

Reactant 2

HCID 6058CysteamineHCID 3326105-Chloro-3-(chloromethyl)-1,2,4-thiadiazole

Product 1

HCID 205674873-[(2-Aminoethyl)thiomethyl]-5-chloro-1,2,4-thiadiazole

Procedure

Reacting 5-chloro-3-chloromethyl-1,2,4-thiadiazole with cysteamine by the procedure of Example 1(i)(c) gives 3-[(2-aminoethyl)thiomethyl]-5-chloro-1,2,4-thiadiazole.

Sources & evidence

ORD record
ord-c82b1a54c1ea4a749d9aa25d47ff3d2c
Source dataset
uspto-grants-1979_05
Patent number
US04154844

Reaction notes

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