HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Bromo-3,3,3-trifluoropropanoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Bromo-3,3,3-trifluoropropanoic acid | HCID 13680306 | — |
| Product | 2-Bromo-3,3,3-trifluoropropanoyl chloride | HCID 54045859 | — |
Reaction Steps
A solution of 2-bromo-3,3,3-trifluoropropanoic acid (5 g.) in thionyl chloride (5 ml.) is refluxed in the steam bath for two hours. The excess thionyl chloride is removed in vacuo, and the residue distilled under reduced pressure to yield 2-bromo-3,3,3-trifluoropropanoic acid chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04154935 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-10ae524558134f8d8f3774ea569f41d4 |
| Source note | uspto-grants-1979_05 |