Phosphoric Acid → HCID 54301983, compound

Participants

Reaction Conditions

Reaction Steps

A cooled solution of XXVII from Step (b) above (0.01 m) in 25 ml 2-propanol (~10° C.) is treated with a solution of potassium hydroxide (3 g) in 25 ml water and is stirred under nitrogen at 10° C. for 2 hours. The reaction mixture is acidified with phosphoric acid and the 2-propanol removed at reduced pressure. The aqueous mixture is extracted with methylene chloride. The extracts are dried (MgSO4) and concentrated to produce the title compound.

Provenance & Evidence