Sodium ethanethiolate → HCID 53913723, compound

HRID 262735Notes

Reaction equation

HRID 262735 reaction equation
C[O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH2:7][C@H:8]3[NH:19][CH2:18][CH2:17][C@@:14]4([C:15]=2[CH:16]=1)[C@H:9]3[CH2:10][CH2:11][O:12][CH2:13]4.[S-]CC.[Na+]>CN(C)C=O>[OH:2][C:3]1[CH:4]=[CH:5][C:6]2[CH2:7][C@H:8]3[NH:19][CH2:18][CH2:17][C@@:14]4([C:15]=2[CH:16]=1)[C@H:9]3[CH2:10][CH2:11][O:12][CH2:13]4

Participants

4

Reactant 2

HCID 4459711Sodium ethanethiolateHCID 13690878HCID 13690878, compound

Product 1

HCID 53913723HCID 53913723, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

3-Methoxy-6-oxamorphinan (VIII) is demethylated using sodium thioethoxide in dimethylformamide by the general procedure of Example 2 to produce the title product.

Sources & evidence

ORD record
ord-37deeeb244284cbeb45244887dcf1a29
Source dataset
uspto-grants-1979_05
Patent number
US04154932

Reaction notes

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