反应详情

A mixture of 2.93 g. of 1-amino-3-(4-pyridylmethyl)guanidine hydriodide and 1.34 g. of 2,6-dimethylbenzaldehyde in 5 ml. of glacial acetic acid is heated at 100° C. After 2 hours the solidified reaction mixture is triturated with water and filtered. Crystallization from absolute ethanol gives the desired product as colorless granular crystals, m.p. 197°-200° C.

1. additionA mixture of 2.93 g
2. customAfter 2 hours the solidified reaction mixture is triturated with water
3. filtrationfiltered
4. customCrystallization from absolute ethanol