2,6-Dimethylbenzaldehyde → 1-(2,6-Dimethylbenzylideneamino)-3-(4-pyridylmethyl)guanidine hydriodide

Participants

Reaction Steps

A mixture of 2.93 g. of 1-amino-3-(4-pyridylmethyl)guanidine hydriodide and 1.34 g. of 2,6-dimethylbenzaldehyde in 5 ml. of glacial acetic acid is heated at 100° C. After 2 hours the solidified reaction mixture is triturated with water and filtered. Crystallization from absolute ethanol gives the desired product as colorless granular crystals, m.p. 197°-200° C.

Provenance & Evidence