HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6-Isobutyl-3-methyl-2,4,5,6-tetrahydro-benzo[b]-furan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Pyruvic Acid | HCID 1060 | — |
| Reactant | 3-(2-Methylpropyl)cyclohexan-1-one | HCID 12528502 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 6-Isobutyl-3-methyl-2,4,5,6-tetrahydro-benzo[b]-furan-2-one | HCID 21319605 | — |
Reaction Steps
The process according to claim 1, wherein 3-isobutyl-cyclohexanone and pyruvic acid are heated in an HCl and acetic acid solution to give 6-isobutyl-3-methyl-2,4,5,6-tetrahydro-benzo[b]-furan-2-one and this product is heated for 4 to 5 hours with pyridine hydrochloride to give p-isobutylhydratropic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04154962 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-c2488fbff77043d4841b3b2dea366f46 |
| Source note | uspto-grants-1979_05 |