Catechol → HCID 21317719, compound

HRID 262958Notes

Reaction equation

HRID 262958 reaction equation
[C:1]1([C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4])[OH:2].[Cl:9][CH2:10][C:11](=O)[CH3:12]>>[Cl:9][CH2:10][C:11]1([CH3:12])[O:4][C:3]2[CH:5]=[CH:6][CH:7]=[CH:8][C:1]=2[O:2]1

Participants

3

Reactant 2

HCID 289CatecholHCID 6571Chloroacetone

Product 1

HCID 21317719HCID 21317719, compound

Conditions

Temperature
50 °C

Procedure

110 g (1 mol) of pyrocatechol and 200 ml of chloroacetone were mixed and heated to 50° C. 284 g (2 mol) of phosphoruspentoxide were then added in batches upon strong stirring. The temperature inside the reaction must not exceed 70° C. The mass was then subjected to another hour of stirring whereupon it was decanted and the residue was washed twice with benzene whereupon the united phases were concentrated by evaporation in a rotary evaporator. The mass was then subjected to fractionation in a vacuum (12 torr). The fractions in the boiling range between 104° and 150° C. had a weight of 66 g.

Workup

  1. addition284 g (2 mol) of phosphoruspentoxide were then added in batches upon strong stirring
  2. customThe temperature inside the reaction must not
  3. customexceed 70° C
  4. waitThe mass was then subjected to another hour
  5. customwas decanted
  6. washthe residue was washed twice with benzene whereupon the united phases
  7. concentrationwere concentrated by evaporation in a rotary evaporator

Sources & evidence

ORD record
ord-b21e7fd0a33b4b01b4e74c5d24288079
Source dataset
uspto-grants-1979_05
Patent number
US04155915

Reaction notes

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