HCID 21317706, compound → HCID 21317682, compound

Participants

Reaction Steps

2.2 g of 2-(2-acetylhydrazino)-7-chloro-5-(2-pyridyl)-3H-thieno[2,3-e]-1,4-diazepine are refluxed for 2 hours in 120 ml of absolute xylene. The solution is then cooled and the precipitated impurities are filtered off. The solvent is evaporated under reduced pressure and there is obtained 2-chloro-9-methyl-4-(2-pyridyl)-6H-thieno[3,2-f]-s-triazolo[4,3-a][1,4]diazepine in the form of a crystalline product which, after recrystallization from ethyl acetate, melts at 174°-176° C.

Provenance & Evidence