反应详情

温度

165 °C

A mixture of 19.1 parts of N-phenyl maleic acid monoamide 8.8 parts of N,N'-dimethyl urea and 100 parts of cresol is stirred for 2.5 hours at 165° C. The solvent is distilled off in vacuo and the residue fractionated. An oily liquid distills over at a boiling point of from 220° to 223° C./0.1 Torr and solidifies after a while. Recrystallisation from n-propanol gives the compound confirmed by IR- (bands characteristic of hydantoins at 1705 and 1765 cm-1 and of amide at 1690 cm-1) and NMR-spectra.

1. distillationThe solvent is distilled off in vacuo
2. distillationAn oily liquid distills over at a boiling point of from 220° to 223° C./0.1 Torr
3. customRecrystallisation from n-propanol
4. customgives the compound