Acrylonitrile → 3-[(3-Hydroxypropyl)amino]propanenitrile

HRID 263172Notes

Reaction equation

HRID 263172 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][OH:5].[C:6](#[N:9])[CH:7]=[CH2:8]>>[C:6]([CH2:7][CH2:8][NH:1][CH2:2][CH2:3][CH2:4][OH:5])#[N:9]

Participants

3

Reactant 2

HCID 7855AcrylonitrileHCID 90863-Amino-1-propanol

Product 1

HCID 135569403-[(3-Hydroxypropyl)amino]propanenitrile

Procedure

A solution of 75 g. (1 mole) of 3-aminopropanol is stirred while 54 g. (1 mole) of acrylonitrile is added dropwise. After being allowed to stand at room temperature for several hours and preferably overnight, the reaction mixture is concentrated under reduced pressure at 50° yielding 3-(2-cyanoethyl)aminopropanol.

Workup

  1. concentrationthe reaction mixture is concentrated under reduced pressure at 50°

Sources & evidence

ORD record
ord-6c18ed7a1465480899fe070bc71a7c5b
Source dataset
uspto-grants-1979_05
Patent number
US04156693

Reaction notes

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